Wednesday, 13th November ASSCR, AGCTS, ISCT ANZ and Friends Joint Scientific Conference 2019

This session is supported by: 

• Modelling Human Development with Pluripotent Stem Cells - Amander T Clark
• USING HUMAN EMBRYONIC STEM CELL MODELS OF MITOCHONDRIAL DISEASE TO IDENTIFY CANDIDATE DRUG TREATMENTS - Cameron L McKnight
• An AGM-on-a-chip model for study definitive haematopoiesis and vascular development from hPSCs. - Jingjing Li
• Conserved Epigenetic Regulatory Logic Infers Genes Governing Cell Identity - Enakshi Sinniah
• Probing the neurodevelopmental origins of intellectual disability with human stem cell derived organoids. - Ernst Wolvetang

• In vivo genome editing of primary human hepatocytes: towards a universal, mutation-independent, therapy for metabolic liver disease - Samantha L Ginn
• Could exon skipping become a treatment for recessive Ullrich Congenital Muscular Dystrophy - May T. Aung-Htut
• Reprogramming Cardiomyocytes into Pacemaker Cells Using Gene Therapy - Melad Farraha
• Modelling the neurodegenerative disorder Huntington's disease by direct cellular reprogramming of adult human fibroblasts - Ruth L Monk
• THE ROLE OF VENTX HOMEOBOX GENE DURING HUMAN HAEMATOPOIETIC DEVELOPMENT - Ana Rita Leitoguinho
• It takes two to tango: testing a dual AAV gene therapy approach for Usher syndrome. - Livia Carvalho

• Organoids as a model for colorectal cancer: the first 50 patient lines - Rebekah M Engel
• Resistance to the chemotherapeutic drug 5-FU is associated with a stem cell signature in patient-derived colorectal cancer organoids   - Wing Hei Chan
• Human iPSC-derived vascularised and innervated cardiac organoids for disease modelling - Jarmon G Lees
• The Cell Surface Receptor LRP1 Regulates the Inflammatory and Myelinating Response of Oligodendrocyte Progenitor Cells in the Adult Brain - Kaylene M Young
• Drug screening for cardiac regeneration using human pluripotent stem cell-derived cardiac organoids. - Enzo Porrello

• Immunosuppression Free Human Beta Cell Therapy for Type-1-Diabetes Using a Bioengineered Device. - Bernard E Tuch
• Cell therapy for blood cancer – Delivering on the promise - Siok Tey
• Clinical Phase Development of Cell Therapy - Real world experience in lung transplantation - Daniel Chambers
• The Canadian Experience with Premature Stem Cell Markets and the Regulation of Advanced Regenerative Medicines.  - Ubaka Ogbogu

• Targeting KDM6A as a novel therapeutic strategy for treating craniosynostosis in children with Saethre-Chotzen syndrome - Clara Pribadi
• Pentose phosphate pathway is required for L-proline-mediated transition of mouse embryonic stem cells to early primitive ectoderm-like cells - Sally Vuong
• RUNX1 and Group F SOX genes are required at distinct stages for human haematopoietic development - Freya F Bruveris
• Modelling vascular endothelial cell dysfunction in Friedreich’s ataxia using human iPSCs - Jarmon G Lees
• Identification of age-related transcriptional changes in hPSC-derived retinal pigment epithelium cells using single cell RNA-Seq. - Grace E Lidgerwood
• Using induced pluripotent stem cells to model primary open-angle glaucoma (POAG) - Maciej Daniszewski
• The use of direct cell reprogramming to identify novel targets to treat Huntington’s disease. - Amy Chapman
• Assessing the role of Apolipoproteins E using isogenic human induced pluripotent stem cell-derived cerebral organoids. - Damián Hernández
• Generation of mature intestinal stem cells from pluripotent stem cells using transcription factor guided differentiation - Xiaoli Chen
• Integrin αv is a cell surface marker of human pancreatic endocrine cells - Jacqueline V Schiesser
• Multipotent RAG1+ progenitors emerge directly from hemogenic endothelium in human PSC derived hematopoietic organoids. - Ali Motazedian
• Generation of a molecular atlas to define age-related changes to the transcription factor network - Marina Naval Sanchez
• HOPX regulation of cardiomyocyte proliferation and heart regeneration is metabolically dependent - Clayton E Friedman
• Modelling the mitochondrial disease Sengers syndrome using human embryonic stem cells - Yau Chung Low
• Progressing human lens regeneration via lens cell transplantation as an improved childhood cataract treatment - Rachel Shparberg
• Using intestinal organoids to analyse stem cell function in inflammatory bowel disease   - Eva Chan
• Using gastric organoids to investigate how NF-kB1 prevents the development of gastric cancer. - Serena Gallozzi
• Similar pluripotency, immunomodulatory, osteogenic and chondrogenic characteristics of canine induced pluripotent stem cell-derived mesenchymal stem cells and harvested mesenchymal cells - Arash Shahsavari
• Midbrain dopaminergic phenotype and function are regulated by maturation media - Alita A Aguiar
• Quantitative assessment of a human retinal explant model using adeno-associated virus - Slawomir Andrzejewski
• Proteases mediate mesenchymal stem cell homing to tumours and inhibition of metastasis - Sarah K Baird
• Vector stability in stored blood samples - Anna Baoutina
• AAV Testing Kit: fast-track method to identify highly functional AAV variants - Marti Cabanes Creus
• Modelling novel retinal gene variants in patient-derived iPSC-RPE and retinal organoids - Fidelle Chahine Karam
• Using isogenic stem cells to model disease mechanisms of Juvenile Batten disease - Sueanne Chear
• The abundance of adeno-associated viral (AAV) element cap, rather than rep, is the limiting factor in AAV vector packaging. - Kimberley Dilworth
• Human and mouse retinal models, and investigation of adeno-associated virus delivery - Steven S Eamegdool
• Biological variation of stem/progenitor cells in menstrual blood from healthy women - Caitlin E Filby
• Clinical Development - Cell and Gene Therapies - Simone Flight
• Characterisation of fibroblasts from an Usher syndrome patient with USH2A mutations and subsequent generation of induced pluripotent stem cell lines - Abbie Francis
• Delivery of microRNAs to manipulate mesenchymal stem cell mechanotransduction and improve osteogenesis of cells encapsulated in a hydrogel - Jess E Frith
• Using hiPSC-derived retinal and inner ear organoids to model Usher pathophysiology.   - Anai Gonzalez Cordero
• Illuminating Stem Cell Differentiation Efficacy Through Single-cell Guided Transcriptional Profiling - Nigel Kee
• Protocadherin 15 regulates oligodendrocyte progenitor cell proliferation and cell-to-cell contact - Yilan Zhen
• Generation of human-induced pluripotent stem cell lines from patients with spontaneous coronary artery dissection  - Keerat Junday
• Molecular & functional characterisation of human induced trophoblast stem cells derived from fibroblasts. - Daniela S Valdes